Dermunol™
Rejuvenation; Just a Drop Away
Skin rejuvenation is just a drop away. The largest organ we as humans possess is our skin, and its health is essential in protecting our other vital organs. Kaire International’s most recent topical product, Dermunol, made from the most potent and high-quality Squalene, is now available to help protect your skin.
The Squalene Story
The wonder of Squalene has been recognized by cultures all over the world. Its amazing moisturizing properties have been noted in Asian and Scandinavian cultures for many years. Dating back over a hundred years ago, fisherman from these areas exposed to cold winds and treacherous conditions found their skin to be cracked, chapped and sore. In a desperate plight to relieve the pain, the shark fisherman applied the oil, Squalene, that had seeped from the liver of their catches- the shark- directly to their faces. Legend has it, these hardy individuals saw remarkable results; in a matter of hours, their skin became supple, smooth and moisturized (1).
Squalene has been a high-demand topical product for a number of decades in Europe, Asia, Scandinavia, and the Mid-East. Over the past decade, cosmetic companies have taken advantage of Squalene’s moisturizing abilities by adding to various products.
In addition to its use as a skin moisturizer, since the early 1900s Squalene has been extracted and used medicinally by doctors in Scandinavia, Asia and the Mid-East. More recently, physicians, engineers, and professors began to examine the effects of this fabulous oil on the human body (2).
Dermunol - A Precious Nutrient
The Squalene in Kaire’s topical shark liver oil product, Dermunol, has been shown to assist the body in building cell networks and provides necessary moisture to the tissues (3).* A single drop of Dermunol covers a large area of skin. Unlike other oils on the market used for moisturizing, Dermunol has a mild fragrance and a consistency lighter that olive oil. When applied to the skin it is not greasy and absorbs quickly. In addition, studies have shown that Squalene can assist the immune system and is an excellent topical treatment for minor cuts, rashes, and abrasions (2).* Squalene is also found naturally in the human body, particularly in skin cells and arteries leading to the cerebral cells (1). In addition, it is found in adipose tissues, skin, skeletal muscle, connective tissues, endocrine organs, lymph nodes, the spleen, the liver, and the large intestine. In nature, it is found in wheat germ, olive oil, and rice bran oil. However, this potent substance is found in abundance only in the livers of deep-sea sharks. Up to 80 percent of the lipid content in the shark liver is Squalene oil. An essential nutrient for human beings, Squalene is important in the body’s defense against undesirable free radicals to which our skin is exposed.
The content of Squalene in the human body changes with age from 1 percent in children to a maximum level of 15-20 percent in adults and then begins to decline after age 40. The oil itself is secreted from the body with unsaturated fatty acids from the sebaceous glands and mixed with sweat, which is emulsified to retain smoothness of the epidermal layer of the skin. The amounts of Squalene people secrete is estimated to be 125 to 47 milligrams per day (3).
Scientifically Squalene
Topically administered Squalene absorbs into the skin and penetrates the cell membranes. Extensive research has shown that the oil has anti-oxidant components and may enhance the body’s ability to transport oxygen to the individual epidermal cells when applied to the skin (4).
Dr. Noguchi, M.D., a specialist in Squalene, believes the cause of most diseases is the lack of oxygen transport to the cells. Because Squalene assists in reoxidizing skin tissues, components of the oil are believed to have healing properties (5).* Laboratory tests have reinforced its value for the human skin. An added benefit of Squalene has been found to be its natural ability to protect the skin from direct ultraviolet (UV) radiation. Studies have shown that Squalene topically applied can significantly decrease the absorption of UV radiation. A study published by the Journal of Toxicological Sciences in 1984 reported that Squalene acts as a filter to UV radiation. Direct application of Squalene to the tissues may prevent harmful rays from penetrating the epidermal layer of the skin (5).*
How is Dermunol Produced?
After the oil is removed from the shark liver, it is separated and then purified. The extraction process is extremely delicate and must be done quickly to ensure purity. First, the deacification of crude shark oil occurs; second, the product undergoes distillation and sponification; third, bleaching and deodorization takes place; and finally, the pure oil extract is poured into sterile barrels for export (7). Every barrel of shark oil leaving the distribution facility is submitted to Kaire’s strict quality-control standards (7). The process in which Squalene is extracted must yield a purity level of at least 96 percent.
Kaire International is dedicated to the preservation of individual shark populations and harvests only abundant species of sharks. The livers of these sharks have many different components, not just Squalene. Unlike Kaire’s Immunol, which contains Alkylglycerols, Dermunol contains only Squalene, a hydrocarbon with unique properties and fragrance. Also unlike Immunol, Dermunol is designed for topical use. Individuals with allergies to fish or fish by-products should not use Dermunol. As with any health care product, please consult your health care professional prior to use.
Informative References:
1) Rukmini C., and Raghuram T. 1989. “Nutritional and Biochemical Reactions to Shark Liver Oil.” Journal of American College of Nutrition, 10 (6):593-601
2) Abe T. 1984. Keys to Japanese Fish Fully Illustrated in Colors. Tokyo, Japan: Hokuryukan.
3) Kayama M., Tsuchiya N., and Judd C. 1969. “The Hydrocarbons of Shark Liver Oils.” Bulletin of the Japanese Society of Scientific Fisheries, 35:7.
4) Picardo M., Aompetta C., De Luca T., Ameantea A., Faggioni A., Nazzaro-Porro M., and Passi S. 1991. “Squalene Peroxides May Contribute to Ultraviolet Light-Induced Immunological Effects.” Photodermatol Photoimmunol Photomed, 8:105-110
5) Kelko O., Takaho W., Ryuichi M., Yoshimura K., Yoshimura Y., and Kazoo I. 1984. “The Possible Role of Squalene and its Peroxide of the Sebum in the Occurrence of Sunburn and Protection from Damage Caused by UV Radiation.” The Journal of Toxicological Sciences, 9:151-159.
6) Yamaguchi T., Nakagawa M., Hidaka K., and Yoshida T. 1985. Potentiation by Squalene of Antitumor Effect of 3-(4-amino 2-mithyl-5pyrimidinyl) Methyl)-1-(chlorethyl) Nitriosourea in a Murine Tumor System.” Japanese Journal of Cancer Research, 76:1021-1026
7) Summers G., Wong R., and Eyres L. 1995. Handling and Processing Shark Livers for the Recovery of Squalene and Diacylglyceryl Ethers, Volume 1. Wellington, New Zealand: Department of Scientific and Industrial Research.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
For more information on this topical and one of the best on the market, email all requests to the following email address: