Significant Increase In Men's Fertility Possible With 90-Day Pycnogenol® Treatment

SIGNIFICANT INCREASE IN MEN'S FERTILITY POSSIBLE WITH 90-DAY PYCNOGENOL® TREATMENT
09/21/2002

CHICAGO, IL, September 20, 2002 - The antioxidant Pycnogenol® (pic-noj-en-all) improved the quality and function of sperm in men with fertility problems by a mean of 38% and 19%, respectively, after only 90 days of use, according to a new landmark clinical trial published today in the Journal of Reproductive Medicine, giving infertile couples new hope and a new alternative to more invasive procedures.

"Up to 60% of infertile couples have difficulty conceiving due to abnormalities in the male's sperm. By taking Pycnogenol® to increase normally functioning sperm naturally, couples may be able to (or potentially) avoid in-vitro fertilization and either enjoy improved natural fertility or undergo less invasive and less expensive fertility-promoting procedures," stated Dr. Scott Roseff, author of the study and Director of the West Essex Center for Advanced Reproductive Endocrinology (W.E. C.A.R.E.) in West Orange, NJ.

The seminal fluid surrounding the sperm is normally rich in antioxidants and protects the sperm from oxidative damage, according to Dr. Roseff, "but in sub-fertile men the seminal fluid, for unknown reasons, may not be protected by these antioxidants."

"We chose Pycnogenol® for the study because it is one of the richest natural sources has been of bioavailable and bioactive antioxidant compounds known. Pycnogenol found to be many times more potent than other known antioxidants like vitamin C and vitamin E. The biological precursors of the oligomeric procyanidins such as catechin and taxifoline are effective and well-known free-radical scavengers," he said.

According to Dr. Roseff, the study clearly shows that taking daily doses of Pycnogenol® resulted in improved sperm quality and function because the natural antioxidant protection was supplemented.

Pycnogenol® is a natural plant extract originating from the bark of the Maritime pine that grows along the coast of southwest France. It represents a unique and natural combination of genetically programmed constant proportions of procyanidins, bioflavonoids and organic acids, making it a super antioxidant. Pycnogenol® is available today in hundreds of dietary supplements and multi-vitamin formulas worldwide.

The study was supported by Horphag Research, the original developers of Pycnogenol®.

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